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ISA-67: Advancing Nuclear Safety Through Proven Instrumentation Standards

The ISA-67 series offers a comprehensive framework, providing facility operators with essential information to enhance the safety, reliability and performance of instrumentation and control systems within nuclear power plants. Developed by industry experts, these standards and technical reports provide proven best practices for equipment installation, setpoint determination, system monitoring and technician certification, helping to maintain compliance and safety across the nuclear sector.

Why the ISA-67 Series of Standards Matter

The ISA-67 series ensures nuclear facilities operate safely and efficiently, fully compliant with industry expectations, thus protecting personnel and infrastructure.

 These standards are essential because they:

  • Safeguard public and environmental health by defining safety margins for nuclear facility system operations
  • Help facilitate regulatory compliance with key industries and governmental bodies, including the NRC and ASME
  • Support accurate instrumentation through defined installation practices, setpoint determination and performance monitoring
  • Promote operational consistency and reliability, reducing the risk of system failures or false readings in critical applications
  • Elevate workforce standards by setting qualifications and certification criteria for technicians working on safety-related systems
  • Help manage uncertainty, offering tools and methodologies to effectively calculate, document and adjust safety margins

Explore the ANSI/ISA-67 Standards

ANSI/ISA-67.01.01-2019 - Transducer and Transmitter Installation for Nuclear Safety Applications

This standard provides detailed requirements and guidance for the proper installation of transducers, transmitters and related instrumentation used in safety-related systems outside the nuclear reactor vessel. This ensures accurate and reliable performance even under the rigorous conditions typical of nuclear power environments, thus supporting the integrity and safety of critical measurement and control.

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ANSI/ISA-67.02.01-2021 - Nuclear Safety-Related Instrument-Sensing Line Piping and Tubing

This standard defines the requirements for designing, installing, and protecting instrument sensing and sampling lines in nuclear safety applications. It outlines methods for monitoring the performance of these instrument channels, covering calibration, response time, and other critical performance factors. The standard applies to channels that measure pressure, differential pressure, temperature or neutron flux.

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ANSI/ISA-67.04.01-2018 (R2025), Setpoints for Nuclear Safety-Related Instrumentation

This standard defines the requirements for designing, installing, and protecting instrument sensing and sampling lines in nuclear safety applications. It outlines methods for monitoring the performance of these instrument channels, covering calibration, response time, and other critical performance factors. The standard applies to channels that measure pressure, differential pressure, temperature or neutron flux.

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ISA-67.06.01-2023 - Performance Monitoring for Nuclear Safety-Related Instrument Channels

This standard guides monitoring and verifying the performance of safety-related instrumentation channels that measure pressure, temperature, differential pressure and neutron flux in nuclear facilities. It supports early detection of degradation, promotes condition-based maintenance and ensures continued accuracy and reliability of critical systems, helping to maintain compliance with nuclear safety requirements and operational standards.

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ISA-67.14.01-2000 - Qualifications and Certification of Instrumentation and Control Technicians

This standard establishes criteria for the qualification and certification of instrumentation and control (I&C) technicians working in nuclear facilities. It defines the minimum requirements for education, experience, training and performance necessary to ensure technicians possess the skills and knowledge to maintain the safety and reliability of nuclear I&C systems. By promoting consistent certification practices, this standard develops and sustains a technically competent workforce, aligned with industry expectations for nuclear safety and operational excellence.

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Technical Reports and Recommended Practices

ISA-TR67.04.09-2005 - Graded Approaches to Setpoint Determination

This technical report guides the application of graded approaches to the evaluation, determination, and documentation of setpoints and interlocks in nuclear safety-related instrumentation. It emphasizes considering uncertainty factors and system significance to ensure that setpoints are accurately calculated, properly justified and technically defensible. By supporting risk-informed decision-making, the report helps maintain the reliability and regulatory compliance of critical control and protection systems.

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ISA-RP67.04.02-2010 - Methodologies for Setpoint Determination in Nuclear Safety Instrumentation

This recommended practice provides clear methods and formulas for calculating total channel uncertainty and setting accurate, reliable setpoints in nuclear safety instruments. It also guides documenting, calibrating, and maintaining these setpoints to ensure their validity, integrity, reliability and regulatory compliance of essential safety systems.

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Purchase the  ANSI/ISA-67 Standards and Technical Reports Bundle and save 8%!

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About the ISA67 Committee

The ISA67 Committee develops industry-leading standards and technical reports that promote safe and effective instrumentation and control practices in nuclear power facilities. The committee's work helps define the criteria, procedures and performance expectations that shape safe nuclear operations.

Want to Get Involved?

Join a community of experts helping shape the future nuclear safety instrumentation. Explore the current members of the ISA67 Committee and discover how you can contribute to this critical effort.

For additional information, please get in touch with the ISA standards team

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*Does not apply to ISA standards that are identical IEC adoptions