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ISA-101: Enhancing Human-Machine Interface Design for Safer, Smarter Automation


The ISA-101 series of standards and technical reports provide a trusted roadmap for designing, implementing, operating and maintaining Human Machine Interfaces (HMIs) in modern process automation systems. Focusing on improving safety, quality, productivity, and reliability, these standards guide professionals in creating intuitive and high-performance HMIs that empower operators and optimize control.

Why the ISA-101 Series is Important

The ISA-101 standard and technical reports equip organizations with a powerful framework to create robust, user-friendly and performance-driven HMIs. By adopting these standards, teams can:

  • Reduce operator error and improve situational awareness
  • Boost safety and compliance
  • Increase system reliability and operational continuity
  • Promote standardization and scalability across facilities

Key Components of the ISA-101 Standard

ANSI/ISA-101.01-2015 - Human Machine Interfaces for Process Automation Systems

This standard provides a comprehensive framework for designing and managing Human Machine Interfaces (HMIs) in process automation systems. It emphasizes safety, usability and efficiency through a lifecycle approach that spans design, implementation, operation and continuous improvement.

Key focus areas include human-centered design, effective display structures, intuitive user interaction and the importance of operator training. The standard is applicable across continuous, batch and discrete industries and serves as a foundational guide for developing consistent and high-performing HMIs.

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Supporting Technical Reports

ISA-TR101.01-2022 - HMI Philosophy

This technical report expands on ISA-101 by offering practical guidance for developing a comprehensive HMI philosophy. It builds on subclause 4.2.1 of the core standard and provides real-world examples to help organizations create consistent, effective interface strategies. The report supports the full HMI lifecycle, including standardization, design, implementation and ongoing management.

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ISA-TR101.02-2019 - HMI Usability and Performance

This technical report focuses on improving the usability and performance of Human Machine Interfaces to support safe and efficient operations. It provides guidance on designing, auditing, validating and managing changes to HMIs, and encourages customization beyond standard vendor solutions to better meet specific operational needs.

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ISA101 Committee

The ISA101 committee develops best practices for human-machine interfaces in manufacturing environments, focusing on layout, navigation, alarm systems and cybersecurity.

Interested in shaping the future of HMI standards? Membership is open!

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Need More Info?

For questions or additional resources, contact the ISA standards team at standards@isa.org.

Members: View Read-Only Standards in Pub Hub

Standards*—along with InTech archives, white papers, e-books, and more—are now accessible to members in the ISA Pub Hub.

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*Does not apply to ISA standards that are identical IEC adoptions